Senior Scientist I, Bioinformatics

Job Description:

The Senior Scientist I – Bioinformatics will be a PhD-level computational biologist who will work as part of the drug discovery team to enhance the company pipeline of drugs to treat human diseases. The ideal candidate has multi-omics experience that can be leveraged to identify new targets, predictive biomarkers, and pharmacodynamic biomarkers. They have experience analyzing proteomics data corresponding to a treatment and mining functional genomics screening data.

This position will report to the Director of Bioinformatics and can be performed on-site in Lawrence, KS, Waltham, MA, or remotely within the US. This position will require quarterly travel to our research facility in Lawrence, KS.

What You’ll Do:

• Work as part of a collaborative team to apply innovative data analysis approaches
• Perform multi-omic analyses of publicly available data such as DepMap, TCGA, and GEO deposited datasets.
• Mine external and internal genomic screening data, such as CRISPR screens
• Working with Director of Bioinformatics, other R&D colleagues, and the New Targets Task Force to triage potential new targets.
• Working with R&D colleagues, draft manuscripts and presentations for external disclosure of Deciphera information involving preclinical biological data
• Stay up-to-date with relevant scientific literature and incorporate insights into research activities and new technologies and methods
• Effectively work in an interdisciplinary team environment: communicate and plan research with chemists, biologists, and pharmacologists also working on the project
• Adhere to corporate policies including safety, FDA compliance, and regulatory matters

What You’ll Bring:

• PhD and 4+ years of experience in bioinformatics, computational biology, genetics, or related field with a strong background in data science
• Experience performing multi-omic integration and analysis with an emphasis on analyzing proteomics data (required)
• Proficiency in programming languages such as Python and R (required)
• Familiarity with cloud computing platforms such as AWS, Google Cloud, and/or Azure (required)
• Experience working with functional genomics data including CRISPR screening data (preferred)
• Strong knowledge of human genetics, molecular biology, as well as biological pathways and networks
• Experience working with cross functional discovery teams
• Proven track record in the analysis, visualization, and interpretation of genomics and/or functional genomics data
• Excellent communication and presentation skills to both expert and broad audiences

Benefits:

• Competitive salary and annual bonus.
• Comprehensive benefits package including medical, dental, vision insurance, 401(k) retirement plan with company match, and more.
• Generous parental leave and family planning benefits.
• Outstanding culture and opportunities for personal and professional growth.

Apply Now: Join us in our mission to improve the lives of people with cancer. Apply today to become a part of our dynamic team!