Senior AI Software Engineer - Essex Management

Senior AI Software Engineer - Essex Management

US Remote

This position supports "Essex, an Emmes Company". Essex is a biomedical informatics and health information technology-focused consultancy founded in 2009 and headquartered in Rockville, MD. The Essex team comprises experts with extensive experience in strategically developing and managing complex health and biomedical information programs for clients in the Federal Government, research academia, and private sectors. 

Primary Purpose

This is a senior AI Software Engineering role that works as part of the Modern Technology & Engineering (MT&E) team to bring advanced AI and computational modeling expertise to our precision oncology effort. The ideal candidate combines strong experience in deep learning, graph neural networks, natural language processing, and complex algorithm development with large-scale biomedical data integration and a strong understanding of genomics, proteomics, and clinical informatics. As part of our Modern Technology & Engineering (MT&E) team, you will help standardize and analyze complex biological and clinical datasets, develop scalable AI-driven models, and deliver actionable insights that accelerate cancer research and treatment strategies. The role provides a strong career growth opportunity in an innovative technology environment working in one of our nation's premier research organizations.

Responsibilities

• Collaborate with biologists, clinicians, and software engineers to design AI-powered analytics for genomics, proteomics, and clinical data.
• Apply large language models and Retrieval-Augmented Generation (RAG) techniques to make biomedical data interoperable and AI-ready for the National Cancer Institute and related projects.
• Curate, model, and integrate genetic and clinical datasets into standardized, interoperable formats to support precision medicine.
• Work with clinical laboratories to ensure accurate data ingestion into the MATCH processing infrastructure.
• Design, test, and optimize pipelines for variant calling and annotation, leveraging scripting languages (Python, SQL) and modern ML workflows.
• Contribute to the design of intuitive databases and interactive web tools for researchers and clinicians.
• Generate high-quality, interpretable reports for internal and external stakeholders, supporting clinical and research decision-making.
• Work with enterprise-level software system and services for our clients, using Python (or other programming languages)
• Drive and refine AI/ML best practices and processes, as well as provide resolutions to identified issues and bugs.
• Write well-tested and maintainable code leveraging unit, integration, and BDD tests.
• Contribute to project documentation, including architecture diagrams, sequence diagrams, technical documentation and SOPs.
• Participate in SDLC-related planning, standup, review, and retrospective meetings when required.
• Provide leadership support for your project team in the absence of the team lead.
• Work in a collaborative cross-functional team environment to move features (JIRA tasks) across all tiers in a CI/CD Agile SCRUM environment.
• Collaborate with cross-functional teams, when necessary, to complete cross-project initiatives (e.g., common use libraries).
• Put together presentation(s) and be able to present to a technical and non-technical audience. Meet with project stakeholders to discuss technical topics.
• Contribute domain-specific articles to the technical knowledge base to support knowledge sharing across teams.
• Be a proactive part of the MT&E team, looking to broaden and improve our foundational AI/ML capabilities.
• Assist junior staff with task-related or troubleshooting problems.
• Interview technical candidate(s) and provide evaluation/recommendation to the hiring manager.

Qualifications

• Strong communication skills (oral and written).
• Proficient in Python, Java, Ruby, or comparable programming languages.
• D. in Mathematics, Bioinformatics, Computational Biology, or related field.
• Strong track record in machine learning and AI, including deep learning (CNNs, GNNs) for biomedical or complex data applications.
• Experience with ML frameworks (PyTorch/TensorFlow) and code versioning (Git).
• Familiarity with genetic variant standards (HGVS, VCF) and clinical data ontologies.
• Demonstrated success applying AI/ML to biomedical or multi-modal datasets (genomics, proteomics, clinical).
• Demonstrated ability to work cross-functionally and communicate technical results clearly to diverse teams.
• Ability to translate complex data analyses into actionable insights for multidisciplinary teams.
• Track record of publications and innovation in AI-driven data science for life sciences (preferred).

More about The Emmes Group

Emmes Group: Building a better future for us all. 

Emmes Group is transforming the future of clinical research, bringing the promise of new medical discovery closer within reach for patients. Emmes Group was founded as Emmes more than 47 years ago, becoming one of the primary clinical research providers to the US government before expanding into public-private partnerships and commercial biopharma. Emmes has built industry leading capabilities in cell and gene therapy, vaccines and infectious diseases, ophthalmology, rare diseases, and neuroscience. 

We believe the work we do will have a direct impact on patients’ lives and act accordingly. We strive to build a collaborative culture at the intersection of being a performance and people driven company. We’re looking for talented professionals eager to help advance clinical research as we work to embed innovation into the fabric of our company. If you share our motivations and passion in research, come join us! 

Why work at Emmes?

At Emmes, your actions and hard work will have a direct impact on public health initiatives, both globally and in our local communities with opportunities for volunteerism through our  Emmes Cares  community engagement program.   We offer a competitive benefits package focused on the health and needs of our growing workforce, including:

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The Emmes Company, LLC is an equal opportunity employer and does not discriminate in its selection and employment practices. All qualified applicants will receive consideration for employment without regard to disability or protected veteran status.

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