Bioinformatics Engineer 1, Custom Data Report (Temp - 6 months)

Job Description:

At Personalis, we are transforming the active management of cancer through breakthrough personalized testing. We aim to drive a new paradigm for cancer management, guiding care from biopsy through the life of the patient. Our highly sensitive assays combine tumor-and-normal profiling with proprietary algorithms to deliver advanced insights even as cancer evolves over time. Our products are designed to detect minimal residual disease (MRD) and recurrence at the earliest timepoints, enable selection of targeted therapies based on ultra-comprehensive genomic profiling, and enhance biomarker strategy for drug development. Personalis is based in Fremont, California.

Summary:

We are seeking a dedicated and detail-oriented Bioinformatics Engineer to join a team which is focused on delivering a wide range of custom analyses to support the needs of Biopharma customers. This team is responsible for generating immuno-oncology and ultrasensitive MRD/liquid biopsy custom reports based on the specifications provided by the customers. The ideal candidate will be responsible for the retrieval, processing, and formatting of the genomic data based on the provided specifications followed by rigorous quality control of the generated report.

Duration: 6 months

Days onsite: Remote

Responsibilities:

• Work with our existing frameworks to execute custom report generation.
• Work within a team scrum context to ensure timely delivery across multiple concurrent projects.
• Perform detailed QC of the generated reports to ensure all of the content meets the customers' specifications prior to delivery.
• Using established QC tools for systematically testing the accuracy of generated custom reports to detect hidden errors and irregularities in the data.
• Collaborate with and provide feedback to the Custom Data Report (CDR) team to drive continuous improvement.

Education:

• Minimum BS in Bioinformatics, Computer Science, or a related field. 
• At least 1 year’s experience working in a bioinformatics role. 

Qualifications: 

• Expertise in Python, particularly in using pandas data frames for data wrangling.
• Familiarity with standard bioinformatics NGS data formats and annotations. 
• Obsessed with getting the details right.
• Experience using high-performance compute clusters is a plus.
• Proficiency in Unix/Linux environments and Bash scripting.
• Experience with SQL queries to extract and filter large data sets is a plus. 
• Understanding of different assays and modes of sequencing (WGS vs. Exome, RNA-seq, Tumor vs. Normal, Somatic vs. Germline, etc.).
• Understanding of  NGS biomarkers related to cancer (e.g. copy numbers, fusions, SNV and INDELs).
• Experience with Jira, Confluence and Git for version control is a plus. 
• Demonstrated ability to work effectively both independently and collaboratively with other team members.
• Excellent written and verbal communication skills.

Personalis is an equal opportunity employer and is committed to the full inclusion of all individuals. As part of this commitment, Personalis will ensure that persons with disabilities are provided with reasonable accommodations. If you need an accommodation to participate in the job application or interview process, to perform essential job functions, and/or to receive other benefits and privileges of employment, please let your recruiter know, if/when they contact you.

Personalis is an Equal Opportunity Employer/Minorities/Females/Veterans/Disabilities.

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