Systems Engineer II (PCR/qPCR/Sequencing/troubleshhoting)

Our client, a world
leader in biotechnology and gene therapy, is looking for an “Systems
Engineer II” based in Santa Clara, CA.

Job Duration: Long
Term Contract (Possibility Of Extension)

Pay Rate : $57/hr on W2

Company Benefits: Medical, Dental,
Vision, Paid Sick leave, 401K

Client is seeking a
hands-on Systems Engineer II to support the development and integration
of next-generation sequencing (NGS) solutions. This role will work with the Single
Molecule Sequencing platform to optimize workflows, perform wet-lab
experiments, troubleshoot system and assay issues, and support verification and
validation activities.

Key Responsibilities

• Design,
  execute, analyze, and document experiments supporting NGS feasibility,
  development, integration, verification, and validation.
• Perform
  nucleic acid extraction, sample preparation, library preparation, and
  sequencing experiments.
• Optimize
  sequencing workflows and operating protocols.
• Troubleshoot
  instrument, assay, and workflow failures using root cause analysis.
• Develop
  and execute test cases based on product requirements.
• Apply
  statistical analysis and Design of Experiments (DoE) methods to interpret
  data and improve sequencing performance.
• Collaborate
  with assay, instrumentation, software, bioinformatics, and systems
  engineering teams.
• Maintain
  accurate laboratory records and support continuous improvement of
  sequencing performance, reliability, throughput, and reproducibility.

Required Qualifications

• Bachelor’s
  degree with 5+ years of relevant experience, or Master’s degree with 1–3+
  years of relevant experience in science, engineering, chemistry, or a
  related field.
• Hands-on
  experience with PCR, nucleic acid extraction, DNA sequencing, sample
  preparation, library preparation, and/or NGS.
• Experience
  using Python, MATLAB, Git, or similar tools for data analysis or
  automation.
• Knowledge
  of statistical analysis, including JMP, regression, and ANOVA.
• Experience
  with Design of Experiments (DoE) and statistical process control.
• Strong
  troubleshooting, root cause analysis, data analysis, and technical
  documentation skills.

If interested, please
send us your updated resume at

[email protected]/[email protected]