Senior Guideline Specialist
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ASCO
Alexandria, VA, US
Summary
Lead the end-to-end design and execution of clinical practice guidelines and oversee rigorous evidence-based systematic literature reviews. Provide methodological expertise to expert panels and integrate AI-augmented tools to optimize guideline development workflows.
Job Description
Are you interested in making a world of difference in cancer care?
Cancer strikes more than 10 million people worldwide each year. As the leading medical society representing doctors who care for people with cancer, the American Society of Clinical Oncology (ASCO) is committed to conquering cancer through research, education, and promotion of the highest quality care.
Who we are:
ASCO is a flexible, high-performance membership organization where employees collaborate to support our mission through evidence, care, and impact. Together with Conquer Cancer, the ASCO Foundation, we foster a culture that prioritizes customer-centricity, emphasizes teamwork, and commits to quality. Our culture, ASCO Works – Our Way of Working, has long enabled workplace flexibility and embraced technology to help us achieve balance. To learn what it’s like to work at ASCO, click here.
Total Rewards:
At ASCO, we offer a competitive and comprehensive total rewards package. Our compensation philosophy and structure ensure that pay remains market-based, tied to performance, and aligned with our core values. The hiring salary range displayed accounts for a broad spectrum of factors, and the final offer will depend on an evaluation of the selected candidate's experience, training, and specialized skill sets.
In addition to base pay, this position is eligible for our robust total rewards package, which includes health, vision, and dental insurance, a 401(k) with generous contribution, health and wellness benefits, family forming benefits, education support program, generous leave, and much more!
Who we are looking for:
The Senior Clinical Practice Guideline Developer plays a pivotal role in advancing the Society’s strategic mission by leading the lifecycle of ASCO’s evidence-based clinical guidance products. Operating at an advanced level of development expertise, the Senior Developer collaborates with multi-disciplinary teams of global oncology experts to design and execute rigorous, efficient systematic literature reviews. This role is central to modernizing ASCO's methodology through the strategic integration of AI-driven research tools and digital guideline development platforms, enabling the delivery of high-impact clinical practice guidelines, rapid updates, and dynamic "living guidelines.
Responsibilities
· Guideline Development & Methodology: Lead the end-to-end design and execution of clinical practice guidelines and other guidance products. Oversee rigorous evidence-based systematic literature review development—including protocol development, literature search and screening, data extraction, quality appraisal, and report writing—in strict alignment with the ASCO Practice Guideline Methodology Manual.
· Expert Panel Leadership: Provide advanced methodological expertise to guide and support Guideline Advisory Groups, expert panels, and internal working teams throughout the guideline development lifecycle.
· Platform & Technological Innovation: Champion and integrate advanced guideline development platforms and AI-augmented tools to optimize workflows, including literature search and screening, citation management, data extraction, quality appraisal, and evidence synthesis.
· Clinical Tools & Project Delivery: Spearhead the creation of guideline-derived clinical tools, pathways, informatics, and resources to support dissemination, implementation, and evaluation initiatives.
· Process Optimization: Drive continuous quality improvement and standardization initiatives to streamline systematic reviews and accelerate guideline development timelines.
· Strategic Reporting: Deliver expert briefings and reports on guideline content, methodology, and informatics to the Board of Directors, Evidence-Based Medicine Committee, and other key governance stakeholders.
Required Education and Experience
- Education: Master’s degree or higher in a relevant field (e.g., Epidemiology, Public Health, Health Informatics, Healthcare Research, or a related scientific discipline).
- Professional Experience: 5–10+ years of progressive experience in clinical practice guideline development, systematic literature reviews, or evidence-based medicine synthesis.
- Methodological & Publication Expertise: Demonstrated track record of managing technical clinical documents through complex multi-stakeholder review cycles and successfully publishing in peer-reviewed medical journals.
- Advanced Technical Platform Proficiency: Proven experience utilizing and implementing digital guideline authoring platforms, systematic review software, and AI-assisted research tools.
- Information & Content Governance: Strong expertise in content management systems (CMS) and managing large, complex digital libraries of technical and scientific documents.
Preferred Education and Experience
- Previous experience with medical specialty societies or volunteer groups is desirable
Competencies
· AI & Digital Platform Mastery: Advanced capability to leverage modern guideline authoring platforms and AI-augmented productivity tools to accelerate data extraction and evidence synthesis, without sacrificing methodological integrity, clinical accuracy, or compliance standards.
· Clinical Diplomacy & Relationship Management: Proven emotional intelligence, professional maturity, and diplomatic tact required to consult, engage, and build consensus among world-class oncology experts and multi-disciplinary panels.
· Strategic Communication & Consensus Building: Exceptional written, verbal, and presentation skills, with a demonstrated ability to synthesize complex scientific data into clear, actionable insights for diverse stakeholder audiences.
· Project Governance & Execution: Elite organizational, prioritization, and time-management skills, with a track record of managing competing priorities, meeting stringent deadlines, and maintaining meticulous attention to detail across complex, multi-phase projects.
· Analytical & Critical Thinking: Superior problem-solving and analytical capabilities to evaluate conflicting clinical data, navigate methodological ambiguity, and drive sound, evidence-based conclusions.
ADA/Physical Requirements
Extended periods seated or standing at a desk.
High use of computer and other office technology equipment.
Travel
1-10 days/yr
Remote Eligible
Yes
Founded in 1964, the American Society of Clinical Oncology (ASCO) is committed to making a world of difference in cancer care. As the world’s leading organization of its kind, ASCO represents more than 50,000 oncology professionals who care for people living with cancer. Through research, education, and promotion of the highest quality care, ASCO works to conquer cancer and create a world where cancer is prevented or cured, and every survivor is healthy. ASCO’s Conquer Cancer Foundation supports the Society by funding groundbreaking research and education across cancer’s full continuum. Learn more at www.ASCO.org.
Use of our LinkedIn page is subject to our Social Media Policy (http://www.asco.org/about-asco/legal/social-media-policy) as well as applicable policies of LinkedIn
Founded
1964
Company size
201-500 employees
Industry
Non-profit Organizations
Org type
Nonprofit
Headquarters
Alexandria, VA
Founded in 1964, the American Society of Clinical Oncology (ASCO) is committed to making a world of difference in cancer care. As the world’s leading organization of its kind, ASCO represents more than 50,000 oncology professionals who care for people living with cancer. Through research, education, and promotion of the highest quality care, ASCO works to conquer cancer and create a world where cancer is prevented or cured, and every survivor is healthy. ASCO’s Conquer Cancer Foundation supports the Society by funding groundbreaking research and education across cancer’s full continuum. Learn more at www.ASCO.org.
Use of our LinkedIn page is subject to our Social Media Policy (http://www.asco.org/about-asco/legal/social-media-policy) as well as applicable policies of LinkedIn
Founded
1964
Company size
201-500 employees
Industry
Non-profit Organizations
Org type
Nonprofit
Headquarters
Alexandria, VA