Senior Director, Global Pricing Execution

Revolution Medicines is a global, commercial-state oncology company dedicated to discovering, developing and delivering innovative medicines for patients with RAS-addicted cancers. Leveraging its differentiated RAS(ON) tri-complex inhibitor platform, the company is advancing a broad, integrated portfolio of oral RAS(ON) inhibitors designed to directly target the active, cancer-driving state of RAS. Founded on rigorous scientific inquiry and a willingness to challenge long-held assumptions, Revolution Medicines is committed to changing the trajectory of disease for patients with RAS-addicted cancers worldwide.

Our people are united by a shared way of working: follow the science, challenge assumptions, act with urgency and hold ourselves to a high standard of rigor—all in service of patients.

The Opportunity:

Revolution Medicines is seeking a strategic, collaborative, and execution-oriented Senior Director, Global Pricing Strategy & Execution to build and lead global pricing capabilities and support the execution of strategies to support our emerging oncology portfolio. This leader will establish the frameworks for  pricing and contracting strategy for current and future investigational therapies targeting RAS-addicted cancers..

This role will partner closely with Global Market Access, Commercial, Medical Affairs, Finance, Regulatory, Legal, Supply Chain, and Regional/Country teams to translate strategy into compliant, launch-ready execution.

Key Responsibilities

• Establish global pricing architecture, including list-price strategy, country sequencing, price corridors, launch price recommendations, lifecycle pricing, and governance processes.

• Partner with Global Market Access to develop integrated pricing and reimbursement strategies that support value communication, payer engagement, and sustainable patient access.

• Lead development of global price business cases and financial models, including gross-to-net, demand, revenue, access, and affordability scenarios.

• Define pricing guardrails, discounting principles, Innovative Access Agreements (IAAs), approval authorities, and exception-management processes that enable disciplined local execution.

• Partner with regional and country teams to adapt global pricing strategies to local healthcare systems, reference-pricing dynamics, HTA requirements, tender environments, and regulatory constraints.

• Collaborate with Commercial Operations and IT to design and implement fit-for-purpose pricing, contracting, and analytics tools.

• Establish dashboards and operating rhythms to monitor price realization, gross-to-net performance, access outcomes, contracting performance, and pricing risks.

• Support launch readiness planning by ensuring pricing strategy, governance, systems, and cross-functional accountabilities are in place ahead of anticipated approvals.

• Provide thought leadership and clear recommendations to senior executives; communicate complex pricing tradeoffs in a concise, decision-oriented manner.

• Build and develop a high-performing pricing team and foster pricing capabilities across the global organization.

Required Skills, Experience and Education:

• Advanced degree (PhD, PharmD, MD, MBA, or equivalent) in Health Economics, Public Policy, Life Sciences, or related field.

• 12+ years of experience in global pricing, market access, health economics, or government policy within the biopharmaceutical industry.

• Deep understanding of global pricing and reimbursement systems (e.g., US, EU4+UK, Japan, emerging markets).

• Proven track record of influencing senior leadership and driving strategic decisions.

• Strong analytical, strategic thinking, and problem-solving skills.

• Excellent communication and stakeholder management capabilities.

• Demonstrated leadership experience managing high-performing teams.

Preferred Skills:

• Experience with rare diseases, oncology, or specialty pharmaceuticals.

• Familiarity with international reference pricing (IRP), Most-Favoered-Nation (MFN) policy, HTA processes, and value-based pricing models.

Key Competencies

• Strategic mindset with strong business acumen

• Deep analytical and quantitative skills

• Executive presence and communication

• Cross-functional leadership and influence

• Adaptability in a rapidly evolving policy environment

#LI-JW1 #LI-Remote

The base pay salary range for this full-time position for candidates working onsite at our headquarters in Redwood City, CA is listed below. The range displayed on each job posting is intended to be the base pay salary range for an individual working onsite in Redwood City and will be adjusted for the local market a candidate is based in. Our base pay salary ranges are determined by role, level, and location. Individual base pay salary is determined by multiple factors, including job-related skills, experience, market dynamics, and relevant education or training.

Please note that base pay salary range is one part of the overall total rewards program at RevMed, which includes competitive cash compensation, robust equity awards, strong benefits, and significant learning and development opportunities.

Revolution Medicines is an equal opportunity employer and prohibits unlawful discrimination based on race, color, religion, gender, sexual orientation, gender identity/expression, national origin/ancestry, age, disability, marital status, medical condition, and veteran status.

Revolution Medicines takes protection and security of personal data very seriously and respects your right to privacy while using our website and when contacting us by email or phone. We will only collect, process and use any personal data that you provide to us in accordance with our CCPA Notice and Privacy Policy. For additional information, please contact [email protected].

Base Pay Salary Range$232,000—$290,000 USD

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