Senior Scientist I

Make your mark for patients

We are seeking a motivated new PhD or experienced BS/MS scientist to be an integral member of the Cambridge, MA Chemistry group as a Scientist I or II – Peptide Chemistry, responsible for using our powerful mRNA display peptide discovery platform to identify and engineer novel ligands of target proteins that are implicated in human diseases with unmet medical needs.  The lab-based position will be part of our peptide chemistry group. The scientist will work closely with medicinal chemistry and DNA encoded library groups to develop new synthesis and screening technologies on and off beads.  The successful candidate will be a skilled experimentalist with deep knowledge of peptide chemistry and synthesis.

Responsibilities:

• Synthesize polypeptides with automated peptide synthesizers or manually.  Workup, purify and deliver those peptides for biological assays.  Design drug-like peptide molecules utilizing medicinal chemistry knowledge, including property-based optimization, and an understanding of ADME, pharmacokinetics and optimal physicochemical properties.
• Design and synthesize peptide conjugates with other therapeutic agents.
• Develop and implement new methods to advance our peptide drug discovery efforts.
• Ensure optimal interaction, communication and provide regular updates on project status to the program leads and leadership team.
• Participate in new target identification and validation
• Triage screening hits, and carry out hit to lead
• Learn to independently lead programs with the goal of delivering of drug candidates

Required Skills:

• Proficient in peptide chemistry design, synthesis, purification, characterization, bioconjugation technologies
• Deep knowledge and experiences in solid phase peptide synthesis
• Experience with chromatography and mass spectrometry data analysis, method development, and applications
• Scientist I = PhD with 0 to 2 years of post-doc industry experience or an MS with 6+ years or a BS with 8+ years of industry experience
• Scientist II = PhD with 2+ years of post-doc industry experience or an MS or BS with 10+ years of industry experience

Base Comp Range:  $99,200 to $130,200  

Are you ready to ‘go beyond’ to create value and make your mark for patients? If this sounds like you, then we would love to hear from you! 

About us 
UCB is a global biopharmaceutical company, focusing on neurology and immunology. We are over 9.000 people in all four corners of the globe, inspired by patients and driven by science. 

Why work with us? 
At UCB, we don’t just complete tasks, we create value. We aren’t afraid to push forward, collaborate, and innovate to make our mark for patients. We have a caring, supportive culture where everyone feels included, respected, and has equal opportunities to do their best work. We ‘go beyond’ to create value for our patients, and always with a human focus, whether that’s on our patients, our employees, or our planet. Working for us, you will discover a place where you can grow, and have the freedom to carve your own career path to achieve your full potential. 

At UCB, we’ve embraced a hybrid-first approach to work, bringing teams together in local hubs to foster collaborative curiosity. Unless explicitly stated in the description or precluded by the nature of the position, roles are hybrid with 40% of your time spent in the office.

UCB is an equal opportunity employer. All employment decisions will be made without regard to any characteristic protected by applicable federal, state, or local law. UCB invites you to voluntarily self-identify during the application process. Provision of self-identification information is entirely voluntary and a decision to provide or not provide such information will not have any effect on your application for employment, your employment with UCB, or otherwise subject you to any adverse treatment. Any information you provide will be considered confidential and will be kept separate from your application and/or personnel file and will only be used in accordance with applicable laws, orders, and regulations.

 
Should you require any adjustments to our process to assist you in demonstrating your strengths and capabilities contact us on [email protected] for application to US based roles. Please note should your enquiry not relate to adjustments; we will not be able to support you through this channel.