Principal Design System Designer

Twin Health 

At Twin Health, we empower people to improve and prevent chronic metabolic diseases, like type 2 diabetes and obesity, with a new standard of care. Twin Health is the only company applying AI Digital Twin technology exclusively toward metabolic health. 

We start by building a dynamic model of each person’s metabolism — drawing on thousands of data points from CGMs, smartwatches, and meal logs — that maps their personal path to better health. Guided by a dedicated clinical care team, our members have lowered their A1C below the diabetes range, achieved lasting weight loss, and reduced or even eliminated medications, all while living healthier, happier lives.

Working here 

Our team at Twin Health is passionate, talented, and united by a shared purpose: to improve the metabolic health and happiness of our members. We believe in empowering every Twin to make a meaningful impact for our members, our clients, and each other, while enjoying a supportive, collaborative work environment.

Twin has been recognized not only for our innovation but also for our culture, including: Innovator of the Year by the Employer Health Innovation Roundtable (EHIR), selected to CB Insights’ Digital Health 150, and named one of Newsweek’s Top Most Loved Workplace® .

With more than $100 million raised in recent funding, including a $53 million Series E round in 2025 led by Maj Invest, and a $50 million investment in 2023 led by Temasek, Twin is scaling rapidly across the U.S. and globally. Backed by leading venture firms like ICONIQ Growth, Sequoia, Sofina, Temasek, and Peak XV, we are building the most impactful digital health company in the world.

Join us as we reinvent the standard of care in metabolic health.

Opportunity

At Twin Health, we are on a mission to leverage the power of AI and advanced technology for the ultimate good: fundamentally transforming human health and well-being. To scale this monumental impact, we need a visionary Principal Design System Designer to write the visual and interactive DNA of our future.

This is not a maintenance role—this is a defining new era for our company, and you are arriving at the inflection point. Reporting directly to the Head of Design, you will lay the architectural bedrock that dictates how fast we move, how beautifully we build, and how deeply we impact lives for years to come.

We operate in a fast-paced, high-stakes environment where speed, execution, and responsible innovation are paramount. You won't just be managing a library; you will be making rapid decisions and putting them to work immediately. By building a world-class, future-proof design system, you will empower our entire product and engineering organization to deliver life-changing experiences to the people who need them most. Whether you are building from 0 to 1 or architecting a massive 1 to 10 revamp, you will take the lead in driving the strategy that powers our mission.

Responsibilities 

• Architect the Company's Future: Play a critical role in defining the long-term trajectory of Twin Health's product design system. You aren't just building a system for today; you are creating the strategic blueprint that will support our next decade of growth.
• Speed & Bias for Action: In our fast-paced environment, you will drive rapid iteration and deployment, expertly balancing high-velocity execution with long-term architectural integrity.
• Establish System Governance: Define and maintain clear contribution models, documentation standards, and version control processes so the broader design team can easily adopt, contribute to, and scale the system at a rapid pace without creating fragmentation.
• Exceptional Execution & Craft: Uphold an uncompromisingly high bar for visual design. You know exactly how design patterns impact the broader UX, ensuring that our system is as beautiful, accessible, and inclusive as it is functional. You can independently generate and land on a compelling visual direction from scratch.
• Drive & Measure Adoption: Partner with engineering and product leaders to champion system adoption across the organization. You will be responsible for metrics to measure the system's impact on product quality, engineering velocity, and overall user experience to ensure design translates to real-world results.
• Bridge Design, Code, & AI: Seize the chance to reinvent the bridge between our design and engineering teams. You will be empowered to forge entirely new operational flows, standing at the forefront of industry innovation by safely leveraging AI and Model Context Protocols (MCP) to automate and translate Figma environments directly into production code.
• Strategic Collaboration & Trade-offs: Be a relentlessly open and communicative partner. While you are highly autonomous in driving visual direction and moving quickly, you also know how to collaborate deeply, when to pull back, and how to make the necessary architectural trade-offs to keep cross-functional projects moving forward.
• Other duties as assigned

Qualifications 

• 8-10 years of experience as a system designer. 
• Experience: A proven track record as a Principal Designer who has successfully built a 0–1 design system or led a massive overhaul of an existing one at scale within a top-tier, fast-paced tech environment.
• Visual & Systems Excellence: An outstanding portfolio that demonstrates exceptional execution and visual craft, inextricably linked with deep, scalable, and systematic thinking.
• Multi-Platform Architecture: Experience designing scalable systems that translate seamlessly across Web desktop, native iOS and Android, understanding the unique technical constraints and native interaction patterns of each.
• Deep Accessibility Expertise: Thorough knowledge of WCAG standards and a proven track record of baking accessibility and inclusive design principles into the core of a design system from day one—because building for the good of human beings means building for everyone.
• Rapid Prioritization & Decisiveness: The ability to navigate ambiguity, weigh complex architectural trade-offs quickly, and prioritize roadmap items that deliver the most immediate, scalable value to the broader team without slowing down momentum.
• Technical Fluency: Deep understanding of front-end constraints and modern tooling. You have developed seamless handoff flows with engineering and have hands-on experience using AI-driven design ops (like Figma MCP servers or AI IDEs) to tweak code, manage variables, and automate documentation directly.
• Mission-Driven Leadership: A history of proactively taking the lead on complex initiatives, making the team around you stronger, and guiding projects across the finish line with speed, low ego, and a passion for building technology that genuinely helps people.
• This remote opportunity based out of the U.S. Applicants must be authorized to work for any employer in the U.S. We are unable to sponsor or take over sponsorship of an employment Visa at this time.

Compensation and Benefits

The compensation range for this position is $220,000 - $230,000 annually. 

Twin has an ambitious vision to empower people to live healthier and happier lives, and to achieve this purpose, we need the very best people to enhance our cutting-edge technology and medical science, deliver the best possible care, and turn our passion into value for our members, partners and investors. We are committed to delivering an outstanding culture and experience for every Twin employee through a company based on the values of passion, talent, and trust. We offer comprehensive benefits and perks in line with these principles, as well as a high level of flexibility for every Twin

• A competitive compensation package in line with leading technology companies
• A remote and accomplished global team
• Opportunity for equity participation 
• Unlimited vacation with manager approval
• 16 weeks of 100% paid parental leave for delivering parents; 8 weeks of 100% paid parental leave for non-delivering parents
• 100% Employer sponsored healthcare, dental, and vision for you, and 80% coverage for your family; Health Savings Account and Flexible Spending Account options
• 401k retirement savings plan

Salary range for US jobsUS Salary Range$220,000—$230,000 USD

We have been made aware of fraudulent interview requests being sent using the Twin Health's name. All communications will come from official Twin Health channels and a twinhealth.com email address. We will never ask you to complete a text interview or request financial details during the interview process.