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Home Flexible Job Board Executive Director, Trade Relations

$314,000–368,000/yr 2d ago

Executive Director, Trade Relations

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Bicara Therapeutics

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Full-time Permanent Remote

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Summary

The Executive Director will design and execute enterprise trade and patient-support strategies to ensure successful product launch readiness. They will lead cross-functional teams and manage strategic partnerships with distributors, pharmacies, and GPOs to optimize market access.

Job Description

Position Overview

The Executive Director, Trade Relations serves as Bicara's senior leader for trade and patient-support strategy ahead of the commercial launch of ficerafusp alfa (FICERA). Reporting to the SVP, Market Access, this role is accountable for designing and executing the enterprise trade strategy across distribution, GPOs, patient support programs, and strategic partners. The Executive Director drives cross-functional alignment, ensures channel readiness, and establishes the frameworks required for compliant, efficient, and high-performing trade operations, partnering closely with Finance, Marketing, Legal, Compliance, Commercial Operations, Supply Chain, Regulatory, and Market Access to deliver a best-in-class customer experience.

This role is remote; 50%+ travel is required, including regular travel to Bicara's Boston office.

Responsibilities

  • Product Launch Readiness: Gather and synthesize all critical trade, distribution, and patient-support inputs required to ensure a successful new-product launch.

  • Trade & Patient Support Strategy: Design and execute comprehensive trade and patient-support strategies that optimize access and the overall patient experience.

  • GPO Contracting Leadership: Develop and implement contracting strategies with Group Purchasing Organizations to strengthen market access and align with commercial objectives.

  • Team Building & Leadership: Build and lead a high-performing organization across trade operations, patient support, and field reimbursement.

  • Strategic Contract Negotiation: Lead negotiations with specialty distributors, specialty pharmacies, GPOs, and patient-hub partners to secure mutually beneficial agreements that advance corporate goals.

  • Internal SME & Cross-Functional Alignment: Serve as the primary subject-matter expert for trade operations, ensuring internal teams are informed, aligned, and equipped with critical market and channel insights.

  • Operational Problem-Solving: Identify operational risks and opportunities, developing both foundational and innovative solutions to improve efficiency, profitability, and product availability.

  • Competitive Landscape Monitoring: Continuously assess competitive dynamics to anticipate challenges, inform strategy, and capitalize on emerging opportunities.

  • Patient Support Governance: Establish and maintain patient-support policies, business rules, and operational frameworks that ensure compliant, consistent, and high-quality service delivery.

  • Strategic Partner Management: Cultivate strong, trust-based relationships with key external partners to enhance collaboration and long-term value creation.

  • Performance & Budget Accountability: Ensure trade and patient-support strategies are executed effectively and deliver against budget, forecast, and corporate performance targets.

Qualifications

  • Bachelor's degree in a relevant field of study; MBA preferred.

  • 12+ years of pharmaceutical trade, distribution, GPO, patient support, and strategic partner experience required.

  • Pharmaceutical trade and patient-support experience for a launch product required.

  • Launch experience on behalf of a publicly traded company's first market entry preferred.

  • Experience with channel-partner contract negotiation, implementation, execution, and performance monitoring.

  • Strong analytical acumen.

  • Executive presence with a strong sense of accountability.

  • Demonstrated ability to balance multiple projects and priorities.

  • Proven team leadership with seamless cross-functional coordination, supported by strong interpersonal and communication skills.

  • Track record of efficient, effective, solution-oriented multitasking.

  • Cultural alignment with Bicara’s Values of Powered by People for Patients, Adaptive Momentum and Candor that Elevates

  • 50%+ travel required for this role.

Company Overview

Bicara Therapeutics is a clinical-stage biotech company pioneering bifunctional antibodies for targeted tumor modulation. Founded in 2020, we've built a global team of over 100 employees headquartered in Boston, with a clear focus on advancing our lead asset, ficerafusp alfa, or FICERA - a potentially first-in-class bifunctional EGFR-directed antibody combined with a TGF-β ligand trap. Our innovative approach combines tumor-targeting with tumor modulation, where one arm localizes to the tumor while the other serves as a modulator, designed to deliver superior efficacy, improved safety, and enhanced durability directly at the tumor site. FICERA specifically addresses a key challenge in solid tumor treatment by enabling immune cell penetration into tumors, reducing fibrosis and immunosuppression while reversing TGF-β-driven resistance mechanisms - ultimately designed to drive the deep, durable responses that may translate into better outcomes and survival for patients. For more information, please visit www.bicara.com.

Here at Bicara, we believe in building diverse teams and cultivating a culture where all voices are included. We encourage people from all backgrounds to apply.

Bicara Therapeutics is an equal opportunity employer and will not discriminate against any employee or applicant on the basis of age, color, disability, gender, national origin, race, religion, sexual orientation, veteran status, or any classification protected by federal, state, or local law.

About the company

Bicara Therapeutics

Bicara is a clinical-stage biopharmaceutical company committed to bringing transformative bifunctional therapies to patients with solid tumors. Bicara has built a platform designed to facilitate the development of bifunctional therapies that precisely target the tumor and deliver a tumor-modulating payload to the tumor site. This approach was deployed in the development of Bicara’s lead program ficerafusp alfa, formerly BCA101, a bifunctional epidermal growth factor receptor (EGFR) directed monoclonal antibody bound to a human transforming growth factor beta (TGF-β) ligand trap. By combining these two clinically validated targets, ficerafusp alfa has the potential to exert potent anti-tumor activity by simultaneously blocking both cancer cell-intrinsic EGFR survival and proliferation, as well as the immunosuppressive TGF-β signaling within the tumor microenvironment (TME). Ficerafusp alfa directs the TGF-β inhibitor into the immediate TME through the binding of EGFR on tumor cells, which Bicara believes will lead to deep and durable responses and an increase in overall survival, while reducing the potential adverse effects previously associated with systemic TGF-β inhibition. Ficerafusp alfa is being developed in head and neck squamous cell carcinoma, where there remains a significant unmet need, as well as other solid tumor types.

For more information, please visit www.bicara.com

Founded

2020

Company size

51-200 employees

Industry

Biotechnology Research

Org type

Public Company

Headquarters

Boston, Massachusetts

Apply Now

About the company

Bicara Therapeutics

Bicara is a clinical-stage biopharmaceutical company committed to bringing transformative bifunctional therapies to patients with solid tumors. Bicara has built a platform designed to facilitate the development of bifunctional therapies that precisely target the tumor and deliver a tumor-modulating payload to the tumor site. This approach was deployed in the development of Bicara’s lead program ficerafusp alfa, formerly BCA101, a bifunctional epidermal growth factor receptor (EGFR) directed monoclonal antibody bound to a human transforming growth factor beta (TGF-β) ligand trap. By combining these two clinically validated targets, ficerafusp alfa has the potential to exert potent anti-tumor activity by simultaneously blocking both cancer cell-intrinsic EGFR survival and proliferation, as well as the immunosuppressive TGF-β signaling within the tumor microenvironment (TME). Ficerafusp alfa directs the TGF-β inhibitor into the immediate TME through the binding of EGFR on tumor cells, which Bicara believes will lead to deep and durable responses and an increase in overall survival, while reducing the potential adverse effects previously associated with systemic TGF-β inhibition. Ficerafusp alfa is being developed in head and neck squamous cell carcinoma, where there remains a significant unmet need, as well as other solid tumor types.

For more information, please visit www.bicara.com

Founded

2020

Company size

51-200 employees

Industry

Biotechnology Research

Org type

Public Company

Headquarters

Boston, Massachusetts

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