Director, Oncology Clinical Affairs (MD)

For more than 25 years, Corcept has been singularly focused on the science of cortisol, a powerful hormone that when unregulated, can play a role in a broad range of diseases.

Our commercial portfolio includes treatments for hypercortisolism and oncology, and the company has discovered more than 1,000 proprietary selective cortisol modulators and glucocorticoid receptor antagonists. With advanced clinical trials in patients with hypercortisolism, solid tumors, ALS and liver disease, Corcept is unlocking the power of cortisol modulation to help address some of the most devastating diseases patients face today. 

Corcept is headquartered in Redwood City, California. To learn more, visit www.corcept.com.

Corcept is seeking a Director, Oncology Clinical Affairs (MD) to serve as a senior clinical associate within Oncology. This role will report to the President of Oncology and will lead high-level clinical and scientific engagement with external oncology experts and serve as a key bridge between Clinical Development, Medical Affairs, Commercial, Market Access, HEOR, Pharmacovigilance, and Regulatory partners. The Director will help shape and execute the introduction of Lifyorli in clinical practice with primary focus in the US market. This role will support the execution of our medical affairs strategy and serve as the primary point of contact with practitioners seeking peer-to-peer interactions to navigate important medical questions. The Director will also support payer-facing engagement leveraging guidelines. 

Responsibilities:

Clinical Engagement and Support  

• Partner with Medical Affairs leadership to support the execution of medical priorities related to product adoption and long-term integration into clinical practice. Serve as the primary clinical bridge between Clinical Development and go-to-market teams, ensuring clinical expertise is available to support Medical Affairs, Commercial, Market Access, HEOR, and Regulatory activities
• Provide clinical and medical/scientific expertise to support medical affairs priorities, tactical planning, internal training, advisory boards, congress activities, and cross-functional initiatives that advance product adoption and integration into clinical practice
• Identify areas of unmet medical need and work cross-functionally to translate scientific insights into practical clinical guidance that supports physicians, patients, and internal decision-making
• Model and promote Corcept’s key principles, collaborating effectively, embracing possibilities, following the data, and leading by doing, to build a culture of accountability, innovation, and trust

Scientific Engagement and External Leadership  

• Lead high-level peer-to-peer scientific interactions with oncology experts, key opinion leaders (KOLs), clinical researchers, academic centers, and other external medical stakeholders
• Build credibility through balanced scientific exchange around the company’s assets, disease areas, emerging data, unmet needs, and evolving standards of care
• Engage physicians and oncology experts through advisory boards, congress interactions, speaker preparation, and insight-gathering activities to inform medical strategy, education, publications, and evidence planning
• Represent Corcept at key medical conferences and external events as an internal clinical expert and external medical ambassador

Evidence Generation and Data Communication  

• Provide clinical input to post-approval evidence generation activities, including real-world evidence (RWE), investigator sponsored studies (ISS), registries, and other data-generation activities that address clinically meaningful evidence gaps
• Provide clinical review and input into ISS proposals and collaborate with Medical Affairs partners on program design, prioritization, and governance
• Evaluate scientific data, clinical trial results, post-marketing evidence, medical literature, and emerging oncology practice trends to inform internal strategy and external scientific communications
• Support development of accurate, balanced, and compliant scientific, educational, medical information, and promotional review materials in partnership with Medical, Legal, Regulatory, Commercial, and Compliance stakeholders

Guideline, Pathway, and Payer-Facing Scientific Support  

• Provide perspectives in interpreting, anticipating, and influencing clinical guideline updates and treatment pathways, including NCCN, ASCO, and other relevant oncology contexts
• Engage external experts and stakeholders to support appropriate representation of the company’s data in guidelines and treatment pathways translate guideline and pathway changes into clear clinical and business-relevant implications for internal teams
• Partner with Market Access and HEOR teams to align the clinical narrative with payer value propositions, including outcomes, comparative effectiveness, and economic value
• Participate in payer-facing discussions when deep clinical expertise is required, ensuring scientific alignment, balanced communication, and compliance with internal standards

Safety and Supportive Care Guidance  

• Partner with Pharmacovigilance, Clinical Development, and Medical Affairs to develop, refine, and communicate safety-related clinical guidance for assigned asset(s)
• Translate emerging safety data, post-marketing reports, and clinical trial safety findings into practical clinician-facing recommendations, including monitoring strategies, risk mitigation approaches, and adverse event management algorithms
• Contribute to supportive care guidance that optimizes patient tolerability and continuity of therapy while aligning with regulatory requirements, internal safety governance, and real-world oncology practice
• Support safety-related external communications, including responses to KOL inquiries, advisory boards, congress interactions, and other scientific exchanges, while ensuring consistency, balance, and compliance

Preferred Skills, Qualifications and Technical Proficiencies:

• Demonstrated ability to evaluate scientific data, clinical literature, evolving treatment pathways, and oncology practice trends and apply insights to medical, launch, market access, and evidence-generation activities
• Understanding of the U.S. healthcare environment, health technology assessment (HTA) considerations, payer evidence needs, and the pharmaceutical/biotechnology industry
• Strong oral, written, and presentation skills, with the ability to communicate complex clinical concepts clearly to internal and external audiences
• Collaborative, cross-functional leadership style with sound judgment, scientific rigor, and the ability to operate effectively in a launch-focused, evolving environment
• Ability to travel 25-30% or as needed
• Demonstrated ability to evaluate scientific data, clinical literature, evolving treatment pathways, and oncology practice trends and apply insights to medical, launch, market access, and evidence-generation activities
• Understanding of the U.S. healthcare environment, health technology assessment (HTA) considerations, payer evidence needs, and the pharmaceutical/biotechnology industry
• Strong oral, written, and presentation skills, with the ability to communicate complex clinical concepts clearly to internal and external audiences
• Collaborative, cross-functional leadership style with sound judgment, scientific rigor, and the ability to operate effectively in a launch-focused, evolving environment
• Ability to travel 25-30% or as needed
• MD required
• Oncology experience required; gynecologic oncology experience preferred
• 3-5+ years of relevant oncology practice (including fellowship)
• Experience engaging oncology experts, interpreting clinical evidence, and translating complex data into clear scientific and clinical communications

The pay range that the Company reasonably expects to pay for this position is $209,100 – $307,600; the pay ultimately offered may vary based on legitimate considerations, including geographic location, job-related knowledge, skills, experience, and education.

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 Applicants must be currently authorized to work in the United States on a full-time basis.

For information on how Corcept collects, uses, discloses, protects, and otherwise processes personal information and an explanation of the rights and choices available to you with respect to your personal information, please refer to our Privacy Notice link. 

Corcept appreciates the commitment and hard work of all our team members as we strive to discover and develop novel treatments for patients with serious unmet medical needs.

 Please visit our website at: https://www.corcept.com/

Corcept is an Equal Opportunity Employer

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