Associate Scientist I, Quality Control

We are looking for a highly motivated, independent and team-oriented Associate Scientist I to work in our high throughput production lab’s Quality Control (QC) Team responsible for initial sample handling. Main responsibilities include, nucleic acid extractions, initial sample QC, and genotyping on the Illumina Infinium platform. This position reports to the QC Supervisor.

Key Responsibilities

● Carry out procedures associated with DNA & RNA for sequencing platforms, including DNA/RNA sample extraction, quantification & preparation, Illumina Infinium genotyping,

● Assist with library preparation and sequencer operation for Illumina NovaSeq X, Ultima UG100, Oxford Nanopore PromethION, PacBio Revio platforms, as needed;

● Perform quality control of initial samples and sequencing ready final library samples;

● Perform sample nucleic acid extraction with the use of automation (Hamilton Star, KingFisher Flex, QIAcube Connect);

● Process DNA for Illumina microarray platforms with use of automation (Hamilton Star, Tecan, iScan);

● Conduct other laboratory work, as needed;

● Track all work and issues in the appropriate databases and Laboratory Information Management Systems (LIMS);

● Become proficient using NYGC’s LIMS tracking system to accurately perform day-to-day tasks;

● Perform monthly instrument maintenance on laboratory equipment, in accordance to instrument SOPs Equipment maintenance

Requirements & Qualifications

● Bachelors’ degree in Molecular Biology, Biotechnology, Biochemistry or related field, plus laboratory experience in nucleic acid research required;

● 1 year of experience in a molecular biology lab;

● Experience with automated liquid handlers preferred;

● Experience in next-generation sequencing a plus;

● Solid knowledge of molecular biology equipment and related protocols (including RNA and DNA preparation, RNA and DNA quantification, hybridization, PCR, multiplex amplification and bead-based solutions) highly preferred;

● Familiarity with Microsoft Word, Excel, and PowerPoint, preferably with Mac OS;

● Good general laboratory and organizational skills, including the ability to work independently and efficiently are essential;

● Ability to multitask is a must, along with an orientation toward teamwork and cooperation;

● Strong creative thinking and problem-solving skills; and,

● Excellent communication skills required.

Competencies

● Technical and Professional Skills: Consistently demonstrates skills and knowledge relevant for current role; strives to expand the depth and breadth of technical and professional skills; works with a high level of integrity; exhibits focus and discipline; appropriately prioritizes, manages expectations and delivers on commitments.

● Collaborative & Communicative: Models collaboration and teamwork; brings out the best in others; effectively works with all levels, internally and externally; respects and embraces diversity of perspective; communicates clearly and listens carefully; uses good judgment as to what to communicate and when to do so.

● Adaptable & Innovative: Adaptable and embraces change; develops new insights and pursues improvements and efficiency; fosters exchange of new ideas and willing to challenge the status quo; takes initiative and is solution-oriented; engages in work with passion and curiosity.

Salary & Benefits

The pay range for this position is $57,000-67,000 per year; the base pay offered may vary depending on job-related knowledge, skills, and experience.

In addition, NYGC offers a full range of medical, financial, and other benefits as well as generous time off. This includes Medical/Dental/Vision for employees & dependent(s); Vacation, Holidays, Sick, and Other Leave, including a paid winter break; a 401(k) match; Life Insurance; Flexible Spending Accounts; employee Tuition Reimbursement; flexible schedules and telework options for some positions; an Employee Assistance Program; and much more.

About the New York Genome Center

The New York Genome Center (NYGC) is an independent, nonprofit, academic research organization dedicated to advancing genomic research. NYGC scientists and staff are furthering new approaches to diagnosing and treating neurological diseases and cancer through their unique capabilities in whole genome sequencing, RNA sequencing, state-of-the art analytics, and the development of genomic tools. NYGC concentrates specifically on disease-based research in the following areas: neuropsychiatric disease (autism, schizophrenia, bipolar); neurodegenerative disease (ALS, Alzheimer’s, Parkinson’s, Huntington’s), and cancer.

Located in Lower Manhattan, the New York Genome Center was founded by and remains closely affiliated with twelve leading academic medical centers and research universities in the New York region and beyond, engaging in research projects with and for these institutions. Essential to our collaborative work is an outstanding faculty, whose members typically hold a joint appointment at NYGC and a partner university. They support our scientific mission by conducting independent research in areas of mutual interest to us and the wider scientific community.

Equal Opportunity

We are committed to fostering a workplace environment that is welcoming and fair to all, ensuring that every employee has the opportunity to thrive. We believe that bringing together

individuals with diverse backgrounds, experiences, and perspectives leads to greater collaboration, innovation, and discovery. Valuing and supporting each employee in reaching their full potential strengthens our organization and enhances our collective success. We recognize that creating an environment where all employees feel valued and included requires sustained effort and dedication from the entire organization.

The New York Genome Center is a VEVRAA Federal Contractor. All qualified applicants will receive consideration for employment and will not be discriminated against on the basis of race, creed, color, gender, religion, national origin, sexual orientation, age, disability, genetic predisposition or carrier status, protected veteran or military status, domestic violence victim status, partnership status, caregiver status, alienage or citizenship status, marital status, or any other characteristic protected by applicable law. NYGC takes affirmative action in support of its policy to hire and advance in employment individuals who are protected veterans and individuals with disabilities.

FLSA Status – Exempt

This position is not eligible for visa sponsorship or relocation assistance.